Peptide Therapy: Weight Loss
Weight-management peptides split into FDA-approved incretin drugs (semaglutide, tirzepatide, liraglutide) available by prescription and investigational ones such as retatrutide, survodutide and mazdutide that are only legally available in trials.
Weight Loss peptides by evidence
| Compound | FDA status | Evidence level | PubMed papers | Tagged trials |
|---|---|---|---|---|
| Liraglutide | FDA-approved | FDA-approved product | 5,683 | 616 |
| Semaglutide | FDA-approved | FDA-approved product | 5,707 | 341 |
| Tirzepatide | FDA-approved | FDA-approved product | 2,637 | 145 |
| L-carnitine | FDA-approved | FDA-approved product | 300 | 36 |
| Tesamorelin | FDA-approved | FDA-approved product | 95 | 23 |
| Cagrilintide | Investigational | Clinical trials / approved abroad | 103 | 15 |
| Tesofensine | Investigational | Clinical trials / approved abroad | 52 | 11 |
| Retatrutide | Investigational | Clinical trials / approved abroad | 202 | 10 |
| Survodutide | Investigational | Clinical trials / approved abroad | 87 | 10 |
| Mazdutide | Investigational | Clinical trials / approved abroad | 54 | 9 |
| O-304 | Investigational | Clinical trials / approved abroad | — | — |
| AICAR | Not approved (research only) | Preclinical or minimal | 2,433 | 18 |
| MOTS-c | Not approved (research only) | Preclinical or minimal | 259 | 5 |
| AOD-9604 | Not approved (research only) | Preclinical or minimal | 22 | 0 |
| Adipotide | Not approved (research only) | Preclinical or minimal | 3 | 0 |
| 5-Amino-1MQ | Not approved (research only) | Preclinical or minimal | 3 | 0 |
| HGH fragment 176-191 | Not approved (research only) | Preclinical or minimal | 1 | 0 |
Label and trial schedules
Reconstitution math
Semaglutide 20 mg vial mathSurvodutide 10 mg vial mathMazdutide 10 mg vial mathRetatrutide 30 mg vial mathAICAR 50 mg vial mathL-carnitine 200 mg vial mathMOTS-c 5 mg vial math5-Amino-1MQ 50 mg vial mathCagrilintide 10 mg vial mathTesamorelin 10 mg vial mathTesamorelin 20 mg vial mathAOD-9604 10 mg vial math
How people access weight loss treatment
Prescription products with an FDA label (the label, not a clinic, sets the approved use and dose):
- Liraglutide: LIRAGLUTIDE (BIOCON PHARMA) LIRAGLUTIDE (BIOCON PHARMA) LIRAGLUTIDE (TEVA PHARMS)
- Semaglutide: OZEMPIC, RYBELSUS (NOVO)
- Tirzepatide: ZEPBOUND, ZEPBOUND (AUTOINJECTOR), ZEPBOUND KWIKPEN (ELI LILLY AND CO) MOUNJARO, MOUNJARO (AUTOINJECTOR), MOUNJARO KWIKPEN (ELI LILLY AND CO)
- L-carnitine: LEVOCARNITINE (DEVA HOLDING AS) LEVOCARNITINE (HIKMA) LEVOCARNITINE (SCIEGEN PHARMS)
- Tesamorelin: EGRIFTA (THERATECHNOLOGIES)
In our clinic directory, 2,835 verified clinics name a related service on their own websites: GLP-1 weight loss 2,835. 1,442 of them mention telehealth. Most listings are in Texas (319), Florida (264), California (189), Arizona (124), Tennessee (120).
Telehealth and clinics
In person: browse verified peptide clinics by state. Compare options: best weight loss peptides by evidence.