Lab arithmeticRetatrutideInvestigational
Retatrutide 30 mg: dosing evidence and reconstitution math
A 30 mg vial of Retatrutide mixed with 2 mL of diluent is 15 mg/mL, so 10 units on a U-100 syringe (0.1 mL) contain 1.5 mg.
Is there an established dose?
Retatrutide has a published dose schedule (trial design); we reproduce it, with its source, on a separate page.
- Retatrutide 12 mg in Phase 3: TRIUMPH Escalation Schedule
- Retatrutide profile: FDA status, research volume and registered trials.
30 mg vial concentration table
Concentration = vial content ÷ diluent volume. A U-100 insulin syringe holds 1 mL in 100 units, so 1 unit = 0.01 mL.
| Diluent | Concentration | Per 10 units (0.1 mL) | Per 1 unit |
|---|---|---|---|
| 1 mL | 30 mg/mL | 3 mg | 300 mcg |
| 2 mL | 15 mg/mL | 1.5 mg | 150 mcg |
| 3 mL | 10 mg/mL | 1 mg | 100 mcg |
| 5 mL | 6 mg/mL | 600 mcg | 60 mcg |
Arithmetic only; it assumes the vial contains exactly what the label states. Independent tests often find vials under- or over-filled, which is why a lot's certificate of analysis matters.
Syringe units for a given amount
Units on a U-100 syringe needed to draw each amount from this 30 mg vial, by diluent volume. The amounts are fractions of the vial (1/50, 1/20, 1/10, 1/5), not dose suggestions.
| Amount | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 600 mcg | 2 units | 4 units | 6 units |
| 1.5 mg | 5 units | 10 units | 15 units |
| 3 mg | 10 units | 20 units | 30 units |
| 6 mg | 20 units | 40 units | 60 units |
Units = amount ÷ concentration × 100. Draws above 100 units exceed a 1 mL syringe.
What the research covers
A PubMed search for "retatrutide"[tiab] returned 202 records (202 from the last five years), 10 indexed as clinical trials when checked on October 2026.
- Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.
- Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial.
- Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA.
- Retatrutide-A Game Changer in Obesity Pharmacotherapy.
- Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials.
ClinicalTrials.gov lists 33 registered studies (search), including:
- Pre-approval Expanded Access of Retatrutide (LY3437943)
- A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
- Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are Overweight
- A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
Where research vials are listed
17 suppliers in our directory list Retatrutide (A–Z): Biocollex Research, BioGenix Peptides, Costides, JetPeps, LotusPeptide, Paramount Peptides, Peptide Crafters, Peptide Partners, and 9 more. Across 17 vendors we checked, the median in-stock price was $5.50/mg (range $1.25–$14.00); see Retatrutide prices per mg. A listing is not a quality endorsement; ask for a lot-specific certificate of analysis.
Storage & handling
Follow the storage statement on the product sheet or certificate of analysis. Lyophilized (freeze-dried) peptides are generally kept cold, dry and away from light; once reconstituted, stability is shorter and depends on the compound and diluent. Bacteriostatic water contains 0.9% benzyl alcohol as a preservative; sterile water does not.
Frequently asked questions
How much bacteriostatic water for a 30 mg Retatrutide vial?
The diluent volume only sets the concentration: 1 mL gives 30 mg/mL, 2 mL gives 15 mg/mL and 3 mL gives 10 mg/mL. Smaller volumes are more concentrated, so each syringe unit holds more.
How much Retatrutide is in 10 units?
At 2 mL of diluent, 10 units (0.1 mL) of a 30 mg vial contain 1.5 mg; at 1 mL they contain 3 mg.
What is the dose of Retatrutide?
Retatrutide has a published dose schedule (trial design); we reproduce it, with its source, on a separate page.
Related pages
Peptide calculator BAC water calculator Retatrutide prices per mg Weight loss & GLP-1 protocols