Peptide Therapy Insights
Are peptides legal in the US?
Approved peptides are legal with a prescription; most 'research peptides' are unapproved drugs. How FDA approval, compounding and RUO labels fit together.
Latest articles
- Bacteriostatic water: what it is and how much to useBacteriostatic water is sterile water with 0.9% benzyl alcohol for multi-dose vials. What the label says, how volume sets concentration, and the math.
- FDA advisers back BPC-157 compounding, 8–6On July 23, 2026 FDA advisers voted 8–6 to recommend BPC-157, TB-500 and KPV for the 503A bulks list. The vote is non-binding; compounding isn't legal yet.
- Reading a peptide COA: six checksA peptide COA should name the lab, lot number, test date, method and result. Here are six checks for HPLC purity, mass-spec identity, endotoxin and lot matching.
- How to store peptidesWhat FDA labels say about storing peptide drugs like Wegovy and Zepbound, and what that implies for powdered and reconstituted research peptides.
- Retatrutide TRIUMPH-2 and -3, in one tableLilly reported up to 20.8% weight loss in TRIUMPH-2 and 22.6% in TRIUMPH-3 at 80 weeks on retatrutide 12 mg. Still investigational; a BLA is planned for Q1 2027.
- Semaglutide dosage, as the Wegovy label sets itWegovy injection: 0.25 mg weekly, rising to 0.5, 1 and 1.7 mg, then 2.4 mg from week 17; 7.2 mg is optional. Tablets reach 25 mg daily by day 91.
- Semaglutide side effects, from the Wegovy labelOn Wegovy 2.4 mg, 44% had nausea vs 16% on placebo, and 73% had a GI effect. Label rates for each common side effect, the serious warnings and the gaps.
- Third-party peptide testing, explainedWhich outside labs peptide vendors name (Janoshik, Vanguard, Freedom Diagnostics, Chromate and more), what their tests show and what they cannot prove.
- Tirzepatide dosage, as the Zepbound label sets itZepbound starts at 2.5 mg weekly for 4 weeks, then 5 mg, rising 2.5 mg at least 4 weeks apart to a 5, 10 or 15 mg maintenance dose. Label-sourced.
- Tirzepatide side effects, by dose, from the Zepbound labelNausea hit 25–29% of Zepbound users vs 8% on placebo; most GI effects came during dose escalation. Every rate below is from the FDA label, with the source linked.
- Wegovy HD 7.2 mg: what FDA approvedFDA approved Wegovy HD (semaglutide 7.2 mg weekly) on March 19, 2026 for adults who have tolerated 2.4 mg for at least 4 weeks and need more weight loss.
- What “research use only” means"Research use only" means a product is not for human or veterinary use and is not made or reviewed as a drug. What that implies for quality and legality.
- The "wolverine stack": BPC-157 and TB-500, checked against the evidenceThe wolverine stack pairs BPC-157 and TB-500 for injury recovery. Neither is FDA-approved, both are banned in sport, and no study has tested the pair.