FDA-approvedGLP-1 receptor agonistWeight losstype 2 diabetes
Liraglutide
Liraglutide is a once-daily GLP-1 receptor agonist, FDA-approved as Victoza and Saxenda; generic versions are available.
What is Liraglutide?
Liraglutide is a once-daily GLP-1 receptor agonist, FDA-approved as Victoza and Saxenda; generic versions are available. Liraglutide is an FDA-approved prescription medicine (LIRAGLUTIDE); "research use only" vials sold online are not the approved product.
Liraglutide is a lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It has a role as a neuroprotective agent and a glucagon-like peptide-1 receptor agonist. It is a polypeptide and a lipopeptide.
Key takeaways
- Liraglutide is an FDA-approved prescription medicine (LIRAGLUTIDE); "research use only" vials sold online are not the approved product.
- PubMed indexes 5,683 papers on Liraglutide (616 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 515 registered studies using Liraglutide.
- No vendor in our directory listed Liraglutide when we checked.
Regulatory & access status
Liraglutide is an FDA-approved prescription medicine (LIRAGLUTIDE); "research use only" vials sold online are not the approved product.
- LIRAGLUTIDE — BIOCON PHARMA, application ANDA215245 (prescription). Drugs@FDA
- LIRAGLUTIDE — BIOCON PHARMA, application ANDA217063 (prescription). Drugs@FDA
- LIRAGLUTIDE — TEVA PHARMS, application ANDA214568 (prescription). Drugs@FDA
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Liraglutide?
PubMed indexes 5,683 papers mentioning Liraglutide in the title or abstract, 2,893 of them from the last five years and 616 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. — N Engl J Med, 2016 · clinical trial
- Liraglutide attenuates type 2 diabetes mellitus-associated non-alcoholic fatty liver disease by activating AMPK/ACC signaling and inhibiting ferroptosis. — Mol Med, 2023
- The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss. — J Clin Invest, 2014
- Liraglutide Promotes Diabetic Wound Healing via Myo1c/Dock5. — Adv Sci (Weinh), 2024
- Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway. — Acta Pharmacol Sin, 2024
- Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial. — JAMA, 2015 · clinical trial
Registered clinical studies
ClinicalTrials.gov lists 515 studies with Liraglutide as an intervention (see all). Most recent:
- Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments. — NCT02244164 · N/A · terminated · started 2014-10
- The Influence of Liraglutide on the Reward Properties of Food: an fMRI Study on Healthy Volunteers — NCT01695109 · Phase 4 · completed · started 2010-11
- Biomarkers in Obese Patients With Knee Osteoarthritis; Weight Maintenance — NCT02928614 · Phase 4 · completed · started 2016-11
- Glucagon-like Peptide (GLP) Utilization and Safety — NCT01767389 · completed · started 2012-09
- Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity — NCT04074161 · Phase 3 · completed · started 2019-09-11
What the evidence does not show
- Paper counts measure research attention, not whether Liraglutide works or is safe.
Research suppliers that list Liraglutide
None of the vendors in our directory listed Liraglutide in their public catalog when we checked. The vendor directory records what each vendor publishes about testing.
Liraglutide reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Liraglutide FAQ
Is Liraglutide FDA-approved?
Liraglutide is an FDA-approved prescription medicine (LIRAGLUTIDE); "research use only" vials sold online are not the approved product.
Is Liraglutide safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Liraglutide?
PubMed indexes 5,683 papers on Liraglutide (616 tagged as clinical trials) as of October 19, 2026.
Who sells Liraglutide?
None of the vendors in our directory listed it when we checked.
Head-to-head comparisons
Related compounds
SemaglutideTirzepatideAICARL-carnitineMOTS-cRetatrutideCagrilintideTesamorelinAll weight loss & glp-1