Source: FDA labelSemaglutide
Semaglutide 2.4 mg: the Wegovy label escalation schedule, step by step
Wegovy label: 0.25 mg weekly for 4 weeks, then 0.5, 1, 1.7 mg, reaching 2.4 mg at week 17. Wegovy HD 7.2 mg only after 4+ weeks at 2.4 mg. Sources linked.
Quickstart highlights
- Five 4-week steps: 0.25 → 0.5 → 1 → 1.7 → 2.4 mg once weekly.
- Maintenance 2.4 mg (1.7 mg if 2.4 mg is not tolerated, per label).
- Wegovy HD 7.2 mg (approved March 19, 2026) is a further step only after at least 4 weeks on 2.4 mg.
Dosing table
| Step | Dose | Duration |
|---|---|---|
| Weeks 1–4 | 0.25 mg | 4 weeks |
| Weeks 5–8 | 0.5 mg | 4 weeks |
| Weeks 9–12 | 1 mg | 4 weeks |
| Weeks 13–16 | 1.7 mg | 4 weeks |
| Week 17 onward | 2.4 mg | Maintenance |
| Wegovy HD (optional) | 7.2 mg | After ≥4 weeks at 2.4 mg |
Protocol overview & notes
The label escalates in four-week steps so that nausea and other GI effects can settle before the next increase. The prescriber decides whether to slow the escalation. The 2.4 mg dose is also the one studied in the STEP 1 trial.
Storage & handling
Follow the storage instructions in the patient information that comes with the pen; brand pens are pre-filled and require no mixing.
How this works & references
Every row of the table above is copied from the source listed below; we change nothing except layout. If the source is revised, we update this page and its date.
Sources
Frequently asked questions
How long does it take to reach 2.4 mg semaglutide on the Wegovy label?
16 weeks of escalation; 2.4 mg starts at week 17 if each step is tolerated.
What comes after 2.4 mg?
For some adults, Wegovy HD 7.2 mg once weekly, approved by the FDA on March 19, 2026, after at least 4 weeks on 2.4 mg when more weight loss is clinically indicated.
Does this page tell me what dose to take?
No. It reproduces the published label schedule for reference. Dosing decisions belong to your prescriber.