InvestigationalGLP-1 / glucagon dual agonistWeight lossMASH
Survodutide
Survodutide (BI 456906) is an investigational once-weekly GLP-1 and glucagon receptor dual agonist from Boehringer Ingelheim in phase 3 trials for obesity and liver disease.
What is Survodutide?
Survodutide (BI 456906) is an investigational once-weekly GLP-1 and glucagon receptor dual agonist from Boehringer Ingelheim in phase 3 trials for obesity and liver disease. Survodutide is an investigational compound: it has been studied in clinical trials but has no FDA approval.
Key takeaways
- Survodutide is an investigational compound: it has been studied in clinical trials but has no FDA approval.
- PubMed indexes 87 papers on Survodutide (10 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 29 registered studies using Survodutide.
- 9 vendors in our directory listed Survodutide in their public catalog on October 19, 2026.
Regulatory & access status
Survodutide is an investigational compound: it has been studied in clinical trials but has no FDA approval.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Survodutide?
PubMed indexes 87 papers mentioning Survodutide in the title or abstract, 87 of them from the last five years and 10 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis. — N Engl J Med, 2024 · clinical trial
- Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity. — Diabetes Care, 2024 · review
- Glucagon and GLP-1 receptor dual agonist survodutide for obesity: a randomised, double-blind, placebo-controlled, dose-finding phase 2 trial. — Lancet Diabetes Endocrinol, 2024 · clinical trial
- Dose-response effects on HbA(1c) and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial. — Diabetologia, 2024 · clinical trial
- Survodutide Once Weekly for the Treatment of Adults with Obesity. — N Engl J Med, 2026 · clinical trial
- Comparison of pharmacological therapies in metabolic dysfunction-associated steatohepatitis for fibrosis regression and MASH resolution: Systematic review and network meta-analysis. — Hepatology, 2025 · review
Registered clinical studies
ClinicalTrials.gov lists 29 studies with Survodutide as an intervention (see all). Most recent:
- A Study to (1) Compare How BI 456906 is Taken up in the Body of Healthy People and People With Liver Problems and (2) Find Out How People With Overweight and Obesity, With and Without Liver Problems, Tolerate Different Doses of BI 456906 — NCT05296733 · Phase 1 · completed · started 2022-04-27
- A Study in Healthy People to Compare How 3 Different Formulations of Survodutide Are Taken up in the Body — NCT06772532 · Phase 1 · completed · started 2025-02-10
- A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight — NCT06066515 · Phase 3 · completed · started 2023-11-25
- A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight — NCT06214741 · Phase 3 · completed · started 2024-02-06
- Albuminuria Reduction Study With Survodutide Treatment in Kidney Disease — NCT07206290 · Phase 2 · not yet recruiting · started 2026-03-02
What the evidence does not show
- Paper counts measure research attention, not whether Survodutide works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list Survodutide
9 vendors in our directory listed a product matching Survodutide in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
- Bulk Peptide Supply
- Eros Peptides
- Extreme Peptides
- Liberty Peptides
- Paramount Peptides
- Plum Labs Research
- Polaris Peptides
- Pure Lab Peptides
- Xcel Peptides
Prices per mg, where we could verify them, are on our price comparison.
Survodutide reconstitution math
Lab arithmetic only, not dosing guidance: vial-by-vial concentration tables are on Survodutide 10 mg vial math.
Survodutide FAQ
Is Survodutide FDA-approved?
Survodutide is an investigational compound: it has been studied in clinical trials but has no FDA approval.
Is Survodutide safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Survodutide?
PubMed indexes 87 papers on Survodutide (10 tagged as clinical trials) as of October 19, 2026.
Who sells Survodutide?
Bulk Peptide Supply, Eros Peptides, Extreme Peptides, Liberty Peptides, Paramount Peptides, Plum Labs Research and 3 more listed it on their public catalogs when we checked; a listing is not an endorsement.
Related compounds
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