Cognitive, neuro & sleep Peptides
14 compounds in this group, 1 of them with an FDA-approved product. Grouping follows what each compound is studied or marketed for; it does not mean the use is proven.
All cognitive, neuro & sleep compounds (A–Z)
| Compound | FDA status | PubMed papers | Last 5 years | Registered trials | Class |
|---|---|---|---|---|---|
| Adamax | Not approved (research only) | 39 | 35 | 0 | Semax analog |
| ARA-290 | Investigational | 14 | 7 | 4 | Erythropoietin-derived peptide |
| Cerebrolysin | Not FDA-approved (approved in some other countries) | 638 | 194 | 43 | Porcine brain peptide preparation |
| Cortagen | Not approved (research only) | 13 | 1 | 0 | Short bioregulator peptide |
| Dihexa | Not approved (research only) | 18 | 6 | 0 | Angiotensin IV analog |
| DSIP | Not approved (research only) | 407 | 4 | 0 | Neuropeptide |
| Fraternine | Not approved (research only) | — | — | 0 | Wasp-venom peptide |
| Oxytocin | FDA-approved | 29,398 | 5,736 | 935 | Neuropeptide hormone |
| P21 | Not approved (research only) | — | — | 0 | CNTF-derived small molecule (P021) |
| PE-22-28 | Not approved (research only) | — | — | 0 | Spadin analog |
| Pinealon | Not approved (research only) | 15 | 1 | 0 | Synthetic tripeptide (Glu-Asp-Arg) |
| Selank | Not FDA-approved (approved in Russia) | 68 | 4 | 0 | Tuftsin analog |
| Semax | Not FDA-approved (approved in Russia) | 209 | 34 | 0 | ACTH(4-10) analog |
| VIP | Not approved (research only) | 8,400 | 883 | 20 | Neuropeptide |
Frequently asked questions
Which cognitive, neuro & sleep peptides are FDA-approved?
1 of the 14 have an FDA-approved product: Oxytocin. Research-grade vials sold online are not those approved products.
Which cognitive, neuro & sleep peptides have the most research?
By PubMed records: Oxytocin (29,398), VIP (8,400) and Cerebrolysin (638). 7 have fewer than 25 indexed papers, mostly cell or animal work.
Which have registered human trials?
4 appear on ClinicalTrials.gov, led by Oxytocin (935), Cerebrolysin (43), VIP (20) and ARA-290 (4). ARA-290 is still investigational.
Comparisons
Reconstitution math
DSIP 10 mg vial mathOxytocin 5 mg vial mathAdamax 5 mg vial mathCortagen 20 mg vial mathCerebrolysin 60 mg vial math
Other categories
Weight loss & GLP-1Growth hormone & GHRHTissue repair & recoveryAnti-aging & longevityBlends & stacksSexual & reproductive healthImmune supportBioregulators & other research compounds
Protocol hub: Cognitive, neuro & sleep protocols and vial math.
Evidence ranking: best cognitive enhancement peptides.