The Peptide Directory

Not FDA-approved (approved in Russia)ACTH(4-10) analogCognitive research

Semax

Semax is a synthetic analog of ACTH(4-10) used in Russia as a nasal drug; it is not approved in the US.

Last reviewed by The Peptide Directory Editorial Team

What is Semax?

Semax is a synthetic analog of ACTH(4-10) used in Russia as a nasal drug; it is not approved in the US. Semax is not approved by the FDA (approved in Russia); products sold online in the US are labeled for research use only.

Key takeaways

  1. Semax is not approved by the FDA (approved in Russia); products sold online in the US are labeled for research use only.
  2. PubMed indexes 209 papers on Semax (4 tagged as clinical trials) as of October 19, 2026.
  3. 43 vendors in our directory listed Semax in their public catalog on October 19, 2026.

Structure

2D chemical structure of Semax (C37H51N9O10S), as depicted by PubChem
Structure: PubChem CID 9811102 (C37H51N9O10S, 813.9 g/mol). 2D depiction from NCBI PubChem, retrieved October 19, 2026.

Amino-acid sequence of Semax, 7 residues: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH

Sequence (7 residues, one-letter code): from the PubChem CID 9811102 record; its molecular formula matches the record's C37H51N9O10S.

Regulatory & access status

Semax is not approved by the FDA (approved in Russia); products sold online in the US are labeled for research use only.

Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.

How much research exists on Semax?

PubMed indexes 209 papers mentioning Semax in the title or abstract, 34 of them from the last five years and 4 tagged as clinical trials (search run October 19, 2026; repeat the search).

Most relevant recent papers

What the evidence does not show

  • Paper counts measure research attention, not whether Semax works or is safe.
  • No FDA review of any "research use only" product's identity, purity, sterility or dose.

Research suppliers that list Semax

43 vendors in our directory listed a product matching Semax in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.

Prices per mg, where we could verify them, are on our price comparison.

Semax reconstitution math

Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.

Semax FAQ

Is Semax FDA-approved?

Semax is not approved by the FDA (approved in Russia); products sold online in the US are labeled for research use only.

Is Semax safe?

Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.

How much research is there on Semax?

PubMed indexes 209 papers on Semax (4 tagged as clinical trials) as of October 19, 2026.

Who sells Semax?

Ascension Peptides, Atomik Labz, Backroad Aminos, Biocollex Research, BioGenix Peptides, BioLongevity Labs and 37 more listed it on their public catalogs when we checked; a listing is not an endorsement.

Head-to-head comparisons

Semax vs Selank

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