Not approved (research only)NeuropeptideImmune / lung research
VIP (vasoactive intestinal peptide)
Vasoactive intestinal peptide (VIP) is a 28-amino-acid neuropeptide; synthetic VIP (aviptadil) has been studied in lung disease.
What is VIP?
Vasoactive intestinal peptide (VIP) is a 28-amino-acid neuropeptide; synthetic VIP (aviptadil) has been studied in lung disease. VIP (vasoactive intestinal peptide) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Key takeaways
- VIP (vasoactive intestinal peptide) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
- PubMed indexes 8,400 papers on VIP (110 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 20 registered studies using VIP.
- 23 vendors in our directory listed VIP in their public catalog on October 19, 2026.
Regulatory & access status
VIP (vasoactive intestinal peptide) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on VIP (vasoactive intestinal peptide)?
PubMed indexes 8,400 papers mentioning VIP (vasoactive intestinal peptide) in the title or abstract, 883 of them from the last five years and 110 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Vasoactive intestinal peptide secreting tumour: An overview. — World J Gastrointest Oncol, 2022 · review
- Vasoactive intestinal peptide. — J Endocrinol Invest, 1986 · review
- Vasoactive Intestinal Peptide-Secreting Tumors: A Review. — Pancreas, 2019 · review
- The role of vasoactive intestinal peptide in pulmonary diseases. — Life Sci, 2023 · review
- A Role for Vasoactive Intestinal Peptide Interneurons in Neurodevelopmental Disorders. — Dev Neurosci, 2021 · review
- Therapeutic potential of vasoactive intestinal peptide and its receptor VPAC2 in type 2 diabetes. — Front Endocrinol (Lausanne), 2022 · review
Registered clinical studies
ClinicalTrials.gov lists 20 studies with VIP (vasoactive intestinal peptide) as an intervention (see all). Most recent:
- Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 — NCT04360096 · Phase 2/Phase 3 · terminated · started 2021-02-15
- Aviptadil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial) — NCT06729606 · Phase 3 · completed · started 2021-04-20
- Yield of Diagnostic Tests and Effects of Crofelemer for Chronic Idiopathic Diarrhea In Non-HIV Patients — NCT03898856 · Phase 4 · completed · started 2019-04-01
- Vasoactive Intestinal Peptide in COPD — NCT00464932 · completed · started 2003-06
- The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients — NCT04260035 · N/A · completed · started 2020-05-19
What the evidence does not show
- Paper counts measure research attention, not whether VIP works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list VIP
23 vendors in our directory listed a product matching VIP in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
- Ascension Peptides
- Atomik Labz
- Biocollex Research
- BioGenix Peptides
- BioLongevity Labs
- Biotech Peptides
- Bulk Peptide Supply
- Core Peptides
- Dynamic Peptide
- Eros Peptides
- Evolve BioPep
- Ion Peptide
- Liberty Peptides
- Licensed Peptides
- Modern Aminos
- NuScience Peptides
- Peptide Crafters
- Peptide Partners
- ProtideHealth
- Royal Peptides
- Science.bio
- Sunrise BioResearch
- Xcel Peptides
Prices per mg, where we could verify them, are on our price comparison.
VIP reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
VIP FAQ
Is VIP FDA-approved?
VIP (vasoactive intestinal peptide) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Is VIP safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on VIP?
PubMed indexes 8,400 papers on VIP (110 tagged as clinical trials) as of October 19, 2026.
Who sells VIP?
Ascension Peptides, Atomik Labz, Biocollex Research, BioGenix Peptides, BioLongevity Labs, Biotech Peptides and 17 more listed it on their public catalogs when we checked; a listing is not an endorsement.
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