InvestigationalErythropoietin-derived peptideNeuropathy research
ARA-290 (cibinetide)
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from erythropoietin, studied in small trials for sarcoidosis-related small-fiber neuropathy.
What is ARA-290?
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from erythropoietin, studied in small trials for sarcoidosis-related small-fiber neuropathy. ARA-290 (cibinetide) is an investigational compound: it has been studied in clinical trials but has no FDA approval.
Key takeaways
- ARA-290 (cibinetide) is an investigational compound: it has been studied in clinical trials but has no FDA approval.
- PubMed indexes 14 papers on ARA-290 (1 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 4 registered studies using ARA-290.
- 26 vendors in our directory listed ARA-290 in their public catalog on October 19, 2026.
Structure
Regulatory & access status
ARA-290 (cibinetide) is an investigational compound: it has been studied in clinical trials but has no FDA approval.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on ARA-290 (cibinetide)?
PubMed indexes 14 papers mentioning ARA-290 (cibinetide) in the title or abstract, 7 of them from the last five years and 1 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis. — Sci Rep, 2017
- Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation. — Cell Transplant, 2021
- The time to develop treatments for diabetic neuropathy. — Expert Opin Investig Drugs, 2021 · review
- Improvement of Islet Allograft Function Using Cibinetide, an Innate Repair Receptor Ligand. — Transplantation, 2020
- A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema. — J Clin Med, 2020
- Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain. — Invest Ophthalmol Vis Sci, 2017 · clinical trial
Registered clinical studies
ClinicalTrials.gov lists 4 studies with ARA-290 (cibinetide) as an intervention (see all). Most recent:
- Study of Efficacy of ARA 290 on Corneal Nerve Fiber Density and Neuropathic Symptoms of Subjects With Sarcoidosis — NCT02039687 · Phase 2 · completed · started 2014-01
- ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes) — NCT01933529 · Phase 2 · unknown · started 2013-10
- Cognitive and Neural Effects of ARA290 — NCT02070783 · Phase 1/Phase 2 · completed · started 2012-02
- The Use of ARA290 for the Treatment of Diabetic Macular Oedema — NCT06626971 · Phase 2 · terminated · started 2016-04
What the evidence does not show
- Paper counts measure research attention, not whether ARA-290 works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list ARA-290
26 vendors in our directory listed a product matching ARA-290 in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
- Ascension Peptides
- Atomik Labz
- Backroad Aminos
- BioGenix Peptides
- BioLongevity Labs
- Biotech Peptides
- Bulk Peptide Supply
- Core Peptides
- Eros Peptides
- Evolve BioPep
- Ion Peptide
- Liberty Peptides
- Modern Aminos
- Paramount Peptides
- Peptide Crafters
- Plum Labs Research
- ProtideHealth
- Pure Lab Peptides
- Royal Peptides
- San Diego Peptides
- Science.bio
- Southern Aminos
- Sunrise BioResearch
- Swiss Chems
- Verified Peptides
- Xcel Peptides
Prices per mg, where we could verify them, are on our price comparison.
ARA-290 reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
ARA-290 FAQ
Is ARA-290 FDA-approved?
ARA-290 (cibinetide) is an investigational compound: it has been studied in clinical trials but has no FDA approval.
Is ARA-290 safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on ARA-290?
PubMed indexes 14 papers on ARA-290 (1 tagged as clinical trials) as of October 19, 2026.
Who sells ARA-290?
Ascension Peptides, Atomik Labz, Backroad Aminos, BioGenix Peptides, BioLongevity Labs, Biotech Peptides and 20 more listed it on their public catalogs when we checked; a listing is not an endorsement.
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