Lab arithmeticCortagenNot approved (research only)
Cortagen 20 mg: dosing evidence and reconstitution math
A 20 mg vial of Cortagen mixed with 2 mL of diluent is 10 mg/mL, so 10 units on a U-100 syringe (0.1 mL) contain 1 mg.
Is there an established dose?
No FDA label or published human trial defines a dose of Cortagen, so we do not publish one. Online "protocols" for it are not evidence.
- Cortagen profile: FDA status, research volume and registered trials.
20 mg vial concentration table
Concentration = vial content ÷ diluent volume. A U-100 insulin syringe holds 1 mL in 100 units, so 1 unit = 0.01 mL.
| Diluent | Concentration | Per 10 units (0.1 mL) | Per 1 unit |
|---|---|---|---|
| 1 mL | 20 mg/mL | 2 mg | 200 mcg |
| 2 mL | 10 mg/mL | 1 mg | 100 mcg |
| 3 mL | 6.667 mg/mL | 667 mcg | 66.7 mcg |
| 5 mL | 4 mg/mL | 400 mcg | 40 mcg |
Arithmetic only; it assumes the vial contains exactly what the label states. Independent tests often find vials under- or over-filled, which is why a lot's certificate of analysis matters.
Syringe units for a given amount
Units on a U-100 syringe needed to draw each amount from this 20 mg vial, by diluent volume. The amounts are fractions of the vial (1/50, 1/20, 1/10, 1/5), not dose suggestions.
| Amount | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 400 mcg | 2 units | 4 units | 6 units |
| 1 mg | 5 units | 10 units | 15 units |
| 2 mg | 10 units | 20 units | 30 units |
| 4 mg | 20 units | 40 units | 60 units |
Units = amount ÷ concentration × 100. Draws above 100 units exceed a 1 mL syringe.
What the research covers
A PubMed search for "Cortagen"[tiab] returned 13 records (1 from the last five years), none indexed as clinical trials when checked on October 2026. That is a very small literature; most of it is cell or animal work.
- Effects of short peptides on lymphocyte chromatin in senile subjects.
- Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray.
- [Cortexin and cortagen as correcting agents in functional and metabolic disorders in the brain in chronic ischemia].
- Tissue-specific effects of peptides.
- The delayed effect of cortagen on the restoration of injured nerve function.
Where research vials are listed
9 suppliers in our directory list Cortagen (A–Z): Atomik Labz, BioGenix Peptides, BioLongevity Labs, Core Peptides, Eros Peptides, Pure Lab Peptides, Swiss Chems, Verified Peptides, and 1 more. A listing is not a quality endorsement; ask for a lot-specific certificate of analysis.
Storage & handling
Follow the storage statement on the product sheet or certificate of analysis. Lyophilized (freeze-dried) peptides are generally kept cold, dry and away from light; once reconstituted, stability is shorter and depends on the compound and diluent. Bacteriostatic water contains 0.9% benzyl alcohol as a preservative; sterile water does not.
Frequently asked questions
How much bacteriostatic water for a 20 mg Cortagen vial?
The diluent volume only sets the concentration: 1 mL gives 20 mg/mL, 2 mL gives 10 mg/mL and 3 mL gives 6.667 mg/mL. Smaller volumes are more concentrated, so each syringe unit holds more.
How much Cortagen is in 10 units?
At 2 mL of diluent, 10 units (0.1 mL) of a 20 mg vial contain 1 mg; at 1 mL they contain 2 mg.
What is the dose of Cortagen?
No FDA label or published human trial defines a dose of Cortagen, so we do not publish one. Online "protocols" for it are not evidence.
Related pages
Peptide calculator BAC water calculator Cognitive, neuro & sleep protocols