Peptide Therapy: Cognitive Enhancement
No peptide is FDA-approved to improve cognition. Semax, Selank and Cerebrolysin are approved in some other countries; DSIP and Dihexa have only early research.
Cognitive Enhancement peptides by evidence
| Compound | FDA status | Evidence level | PubMed papers | Tagged trials |
|---|---|---|---|---|
| Oxytocin | FDA-approved | FDA-approved product | 29,398 | 2,422 |
| Cerebrolysin | Not FDA-approved (approved in some other countries) | Clinical trials / approved abroad | 638 | 89 |
| Semax | Not FDA-approved (approved in Russia) | Clinical trials / approved abroad | 209 | 4 |
| Selank | Not FDA-approved (approved in Russia) | Clinical trials / approved abroad | 68 | 3 |
| ARA-290 | Investigational | Clinical trials / approved abroad | 14 | 1 |
| VIP | Not approved (research only) | Preclinical or minimal | 8,400 | 110 |
| DSIP | Not approved (research only) | Preclinical or minimal | 407 | 17 |
| Pinealon | Not approved (research only) | Preclinical or minimal | 15 | 1 |
| Adamax | Not approved (research only) | Preclinical or minimal | 39 | 0 |
| Dihexa | Not approved (research only) | Preclinical or minimal | 18 | 0 |
| Cortagen | Not approved (research only) | Preclinical or minimal | 13 | 0 |
| P21 | Not approved (research only) | Preclinical or minimal | — | — |
| PE-22-28 | Not approved (research only) | Preclinical or minimal | — | — |
| Fraternine | Not approved (research only) | Preclinical or minimal | — | — |
Reconstitution math
DSIP 10 mg vial mathOxytocin 5 mg vial mathAdamax 5 mg vial mathCortagen 20 mg vial mathCerebrolysin 60 mg vial math
How people access cognitive enhancement treatment
Prescription products with an FDA label (the label, not a clinic, sets the approved use and dose):
In our clinic directory, 1,857 verified clinics name a related service on their own websites: Peptide therapy 1,417; NAD+ therapy 1,174. 994 of them mention telehealth. Most listings are in Texas (243), Florida (213), California (144), Arizona (94), Tennessee (92).
Telehealth and clinics
We have not verified a telehealth provider that lists cognitive enhancement peptides item by item.
In person: browse verified peptide clinics by state. Compare options: best cognitive enhancement peptides by evidence.