Not approved (research only)Cosmetic lipopeptideSkin research
Syn-Coll (palmitoyl tripeptide-5)
Syn-Coll (palmitoyl tripeptide-5) is a cosmetic lipopeptide marketed for collagen support in topical products.
What is Syn-Coll?
Syn-Coll (palmitoyl tripeptide-5) is a cosmetic lipopeptide marketed for collagen support in topical products. Syn-Coll (palmitoyl tripeptide-5) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Key takeaways
- Syn-Coll (palmitoyl tripeptide-5) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
- PubMed indexes 4 papers on Syn-Coll (1 tagged as clinical trials) as of October 19, 2026.
- 2 vendors in our directory listed Syn-Coll in their public catalog on October 19, 2026.
Structure
Regulatory & access status
Syn-Coll (palmitoyl tripeptide-5) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Syn-Coll (palmitoyl tripeptide-5)?
PubMed indexes 4 papers mentioning Syn-Coll (palmitoyl tripeptide-5) in the title or abstract, 3 of them from the last five years and 1 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects. — Colloids Surf B Biointerfaces, 2025
- Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. — Pharmaceuticals (Basel), 2021 · review
- Delivery of Active Peptides by Self-Healing, Biocompatible and Supramolecular Hydrogels. — Molecules, 2023
- Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study. — J Cosmet Dermatol, 2020 · clinical trial
What the evidence does not show
- Paper counts measure research attention, not whether Syn-Coll works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list Syn-Coll
2 vendors in our directory listed a product matching Syn-Coll in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
Prices per mg, where we could verify them, are on our price comparison.
Syn-Coll reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Syn-Coll FAQ
Is Syn-Coll FDA-approved?
Syn-Coll (palmitoyl tripeptide-5) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Is Syn-Coll safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Syn-Coll?
PubMed indexes 4 papers on Syn-Coll (1 tagged as clinical trials) as of October 19, 2026.
Who sells Syn-Coll?
Biotech Peptides, Core Peptides listed it on their public catalogs when we checked; a listing is not an endorsement.
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