GHK-Cu

Structure

What makes GHK-Cu different?

GHK-Cu is one of the few peptides with a long cosmetic history; topical cosmetic use is regulated differently from injectable drug use.

How does GHK-Cu work?

Reviews report that GHK-Cu influences collagen and glycosaminoglycan synthesis, antioxidant responses and the expression of many genes in experimental systems.

What the clinical evidence actually shows

• A 2012 review (Oxid Med Cell Longev) summarizes gene-expression and tissue-remodeling findings, mostly from laboratory and animal work.

How much research exists on GHK-Cu?

PubMed indexes 83 papers mentioning GHK-Cu in the title or abstract, 51 of them from the last five years and 1 tagged as clinical trials (search run October 19, 2026; repeat the search).

Most relevant recent papers

• Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. — Int J Mol Sci, 2018 · review
• The potential of GHK as an anti-aging peptide. — Aging Pathobiol Ther, 2020
• Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians. — Am J Sports Med, 2026 · review
• Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective. — Bioimpacts, 2025 · review
• Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. — J Am Acad Orthop Surg Glob Res Rev, 2026 · review
• Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes? — Molecules, 2025 · review

Registered clinical studies

ClinicalTrials.gov lists 3 studies with GHK-Cu as an intervention (see all). Most recent:

• Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types. — NCT05932732 · Phase 4 · completed · started 2023-11-20
• Two-Part Study of the Effects of the X39 Patch on Circulating GHK and GHK-Cu Levels in Healthy Adults — NCT07706361 · N/A · not yet recruiting · started 2027-01
• Topical GHK-Cu Gel for Acute Skin Wound Healing — NCT07437586 · Phase 2 · recruiting · started 2026-02-02

Side effects

Topical cosmetic use is generally well tolerated in published reports; injectable use lacks controlled human safety data.

Regulatory & access status

• Not an FDA-approved drug. Present in cosmetic products.

Sourcing & safety

Cosmetic products are sold openly; injectable "research" GHK-Cu is not for human use.

Doses in labels and trials

Reference only — copied from published research. Not a recommendation.

What the evidence does not show

• Systemic anti-aging effects in humans.
• Safety of injecting research-grade product.

GHK-Cu FAQ

Related peptides & comparisons

BPC-157TB-500 Injury & Recovery

References

1. The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging, Oxid Med Cell Longev (2012), PMID 22666519
2. GHK-Cu — PubChem compound summary (CID 139035031), PubChem

GHK-Cu calculators

Lab arithmetic only: convert a mass to a volume or syringe units at a known concentration with the units converter, or work out a concentration with the reconstitution calculator.

Where to get GHK-Cu legally

There is no FDA-approved GHK-Cu product. Compounded versions depend on FDA's compounding rules, and "research use only" products are not for human use.

Get GHK-Cu via telehealth

None of the telehealth providers we have verified lists GHK-Cu.

Research suppliers that list GHK-Cu

43 vendors in our directory listed a product matching GHK-Cu in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.

• Amino AmigosCatalog item: “GHK-Cu 100mg”
• Ascension PeptidesCatalog item: “GHK-CU (100MG) 10mL”
• Atomik LabzCatalog item: “GHK-Cu 1g”
• Backroad AminosCatalog item: “GHK-Cu 100mg”
• Biocollex ResearchCatalog item: “GHK-Cu”
• BioGenix PeptidesCatalog item: “GHK-Cu 100mg”
• BioLongevity LabsCatalog item: “GHK-Cu BioStrips”
• Biotech PeptidesCatalog item: “GHK Basic (Tripeptide-1) (200mg)”
• Bulk Peptide SupplyCatalog item: “GHK-CU 100 mg”
• Core PeptidesCatalog item: “GHK-Cu – 200MG”
• CostidesCatalog item: “GHK-Cu 50 mg · 10-pack”
• Eros PeptidesCatalog item: “GHK-Cu (raw powder) 1 Gram”
• Evolve BioPepCatalog item: “GHK-CU 50mg”
• Extreme PeptidesCatalog item: “GHK-CU”
• JetPepsCatalog item: “GHK-cu 50mg”
• Liberty PeptidesCatalog item: “GHK-Cu (Copper Tripeptide) (2mg x 60 Encapsulated Units)”
• Licensed PeptidesCatalog item: “GHK-Cu 100mg (10 vials)”
• LotusPeptideCatalog item: “GHK-Cu 50mg”
• Modern AminosCatalog item: “GHK-Cu 2MG Dry-Fill Units”
• NuScience PeptidesCatalog item: “GHK-Cu 3% Solution with Hyaluronic Acid”
• OmegAminoCatalog item: “OmA – GHK”
• Paramount PeptidesCatalog item: “GHK-Cu (50mg)”
• Peptide CraftersCatalog item: “Raw Powder: GHK-Cu (1000mg)”
• Peptide PartnersCatalog item: “GHK-Cu (100mg vials)”
• Peptide.ExpressCatalog item: “GHK-Cu 50mg”
• Pharma Grade PeptidesCatalog item: “GHK-CU 50MG Copper Peptide”
• Pinnacle Peptide LabsCatalog item: “GHK-Cu [100mg]”
• Plum Labs ResearchCatalog item: “Raw GHK-Cu 1 gram”
• Polaris PeptidesCatalog item: “GHK (Basic) 50mg”
• Prime Lab PeptidesCatalog item: “GHK-Cu – 50mg (10 Vials)”
• Prime PeptidesCatalog item: “GHK-Cu”
• ProtideHealthCatalog item: “GHK-Cu – Copper Peptide”
• Pure Lab PeptidesCatalog item: “GHK-Cu 50mg”
• Ramp PeptidesCatalog item: “GHK-CU Gecko Party Special (COA UNDER MAIN LISTING!) (Copy)”
• Royal PeptidesCatalog item: “GHK-CU 100mgx10vials”
• San Diego PeptidesCatalog item: “GHK-Cu”
• Science.bioCatalog item: “GHK-Cu – Aliquot”
• Southern AminosCatalog item: “GHK-CU RAW POWDER (1g)”
• Sports Technology LabsCatalog item: “GHK-Cu Copper Peptide 50 mg”
• Sunrise BioResearchCatalog item: “GHK-Cu 100mg x 10vials, 1000mg”
• Swiss ChemsCatalog item: “GHK-Cu Copper Peptide”
• Verified PeptidesCatalog item: “GHK-Cu Copper Peptide (100MG)”
• Xcel PeptidesCatalog item: “GHK Basic”

Prices per mg, where we could verify them, are on our price comparison.

GHK-Cu dosing protocol

There is no FDA-label or published-trial dosing schedule we can reproduce for GHK-Cu, so we don't publish one.

Find clinics offering GHK-Cu

• Saguaro Medical Weight Control, semaglutide, phentermineAvondale, AZ — named on the clinic's own website
• Saguaro Medical Weight Control, Semaglutide, PhentermineMesa, AZ — named on the clinic's own website
• Saguaro Medical Weight Control, Semaglutide, PhenterminePhoenix, AZ — named on the clinic's own website
• LaSara Medical GroupCosta Mesa, CA — named on the clinic's own website
• The Shape TheoryLos Angeles, CA — named on the clinic's own website
• iThriveMD of Carmel ValleySan Diego, CA — named on the clinic's own website
• MedArts Weight Loss SpecialistsSan Diego, CA — named on the clinic's own website
• Prime WellnessSan Diego, CA — named on the clinic's own website
• AAI Rejuvenation ClinicFort Lauderdale, FL — named on the clinic's own website
• Dr. Sende Wellness Weight Loss Clinic + PeptidesMiami, FL — named on the clinic's own website
• Dynamink HealthMiami, FL — named on the clinic's own website
• True L.I.O. Health & WellnessMiami, FL — named on the clinic's own website

47 verified clinics name GHK-Cu; browse them by state.

Browse all clinics