Not approved (research only)Cosmetic peptideSkin research
Leuphasyl (pentapeptide-18)
Leuphasyl (pentapeptide-18) is a cosmetic peptide used in topical products marketed against expression lines.
What is Leuphasyl?
Leuphasyl (pentapeptide-18) is a cosmetic peptide used in topical products marketed against expression lines. Leuphasyl (pentapeptide-18) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Key takeaways
- Leuphasyl (pentapeptide-18) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
- PubMed indexes 4 papers on Leuphasyl (0 tagged as clinical trials) as of October 19, 2026.
- 2 vendors in our directory listed Leuphasyl in their public catalog on October 19, 2026.
Structure
Regulatory & access status
Leuphasyl (pentapeptide-18) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Leuphasyl (pentapeptide-18)?
PubMed indexes 4 papers mentioning Leuphasyl (pentapeptide-18) in the title or abstract, 3 of them from the last five years and 0 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Solid Lipid Nanoparticles Incorporated with Retinol and Pentapeptide-18-Optimization, Characterization, and Cosmetic Application. — Int J Mol Sci, 2024
- Pentapeptide-18 as an anti-aging candidate: Spectroscopic characterization and molecular interaction analysis. — Comput Biol Chem, 2026
- D-tyrosine adds an anti-melanogenic effect to cosmetic peptides. — Sci Rep, 2020
- Retinol and Oligopeptide-Loaded Lipid Nanocarriers as Effective Raw Material in Anti-Acne and Anti-Aging Therapies. — Life (Basel), 2024
What the evidence does not show
- Paper counts measure research attention, not whether Leuphasyl works or is safe.
- No clinical trial in humans is tagged in PubMed under this name.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list Leuphasyl
2 vendors in our directory listed a product matching Leuphasyl in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
Prices per mg, where we could verify them, are on our price comparison.
Leuphasyl reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Leuphasyl FAQ
Is Leuphasyl FDA-approved?
Leuphasyl (pentapeptide-18) is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Is Leuphasyl safe?
There are no published human safety trials of Leuphasyl that we could find. Products sold as "research use only" have no FDA review of purity, sterility or dose, and are not for human use.
How much research is there on Leuphasyl?
PubMed indexes 4 papers on Leuphasyl (0 tagged as clinical trials) as of October 19, 2026.
Who sells Leuphasyl?
Biotech Peptides, Core Peptides listed it on their public catalogs when we checked; a listing is not an endorsement.
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