Natural hormone (analogs approved)Hypothalamic hormoneGrowth hormone
GHRH (growth hormone-releasing hormone)
Growth hormone-releasing hormone (GHRH) is the hypothalamic hormone that stimulates growth hormone release; sermorelin and tesamorelin are its analogs.
What is GHRH?
Growth hormone-releasing hormone (GHRH) is the hypothalamic hormone that stimulates growth hormone release; sermorelin and tesamorelin are its analogs. GHRH (growth hormone-releasing hormone) is a natural human hormone; synthetic analogs such as tesamorelin are FDA-approved, but "research use only" products are not.
Key takeaways
- GHRH (growth hormone-releasing hormone) is a natural human hormone; synthetic analogs such as tesamorelin are FDA-approved, but "research use only" products are not.
- PubMed indexes 2,508 papers on GHRH (181 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 95 registered studies using GHRH.
- No vendor in our directory listed GHRH when we checked.
Regulatory & access status
GHRH (growth hormone-releasing hormone) is a natural human hormone; synthetic analogs such as tesamorelin are FDA-approved, but "research use only" products are not.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on GHRH (growth hormone-releasing hormone)?
PubMed indexes 2,508 papers mentioning GHRH (growth hormone-releasing hormone) in the title or abstract, 276 of them from the last five years and 181 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Growth-hormone-releasing hormone. — Clin Chem, 1990 · review
- Growth hormone-releasing hormone. — Endocr Rev, 1986 · review
- Growth Hormone-Releasing Hormone in Endothelial Inflammation. — Endocrinology, 2022 · review
- Growth hormone-releasing hormone and cancer. — Rev Endocr Metab Disord, 2025 · review
- Signaling mechanism of growth hormone-releasing hormone receptor. — Vitam Horm, 2023 · review
- Growth hormone-releasing hormone beyond cancer. — Clin Exp Pharmacol Physiol, 2024
Registered clinical studies
ClinicalTrials.gov lists 95 studies with GHRH (growth hormone-releasing hormone) as an intervention (see all). Most recent:
- Study for Women and Men With Hormone-receptor Positive Locally Advanced or Metastatic Breast Cancer — NCT03096847 · Phase 3 · completed · started 2016-10-24
- Treatment of Children With Insufficient Secretion of Growth Hormone — NCT00271518 · Phase 3 · unknown · started 2005-09
- Clomifene Citrate as First Line Treatment in in Vitro Fertilization Cycles for Patients With Lower Ovarian Reserve — NCT01389713 · N/A · completed · started 2008-09
- Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients — NCT00652379 · N/A · completed · started 2008-06
- Study of Gonadotropin-Releasing Hormone Pulse Frequency in Sexual Maturation and in the Menstrual Cycle — NCT00004335 · completed · started 1993-04
What the evidence does not show
- Paper counts measure research attention, not whether GHRH works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list GHRH
None of the vendors in our directory listed GHRH in their public catalog when we checked. The vendor directory records what each vendor publishes about testing.
GHRH reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
GHRH FAQ
Is GHRH FDA-approved?
GHRH (growth hormone-releasing hormone) is a natural human hormone; synthetic analogs such as tesamorelin are FDA-approved, but "research use only" products are not.
Is GHRH safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on GHRH?
PubMed indexes 2,508 papers on GHRH (181 tagged as clinical trials) as of October 19, 2026.
Who sells GHRH?
None of the vendors in our directory listed it when we checked.
Related compounds
Follistatin-315FollistatinGHRP-6SomatropinHexarelinMGFTesamorelinTesamorelin + CJC-1295 (no DAC) + ipamorelin blendAll growth hormone & ghrh