Not approved (research only)Activin-binding glycoproteinMuscle research
Follistatin
Follistatin is a glycoprotein that binds myostatin and activin; gene-therapy forms have been studied in muscular dystrophy.
What is Follistatin?
Follistatin is a glycoprotein that binds myostatin and activin; gene-therapy forms have been studied in muscular dystrophy. Follistatin is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Key takeaways
- Follistatin is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
- PubMed indexes 2,974 papers on Follistatin (90 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 15 registered studies using Follistatin.
- No vendor in our directory listed Follistatin when we checked.
Regulatory & access status
Follistatin is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Follistatin?
PubMed indexes 2,974 papers mentioning Follistatin in the title or abstract, 671 of them from the last five years and 90 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Follistatin. — Int J Biochem Cell Biol, 1998 · review
- Follistatin and follistatin-like 3 in metabolic disorders. — Prostaglandins Other Lipid Mediat, 2023 · review
- Deletion of fibro-adipogenic progenitors-specific follistatin impairs muscle function and accelerates skeletal muscle atrophy in obese mice. — Mol Med, 2025
- Follistatin: a multifunctional regulatory protein. — Front Neuroendocrinol, 1998 · review
- Follistatin-mediated vascular protection via inhibition of activin A in essential and secondary hypertension. — Hypertens Res, 2024
- Activin/follistatin and atherosclerosis--a review. — J Atheroscler Thromb, 1998 · review
Registered clinical studies
ClinicalTrials.gov lists 15 studies with Follistatin as an intervention (see all). Most recent:
- Possible Sarcopenia, Sarcopenia, and Functional Status in Patients With Primary Sjögren's Syndrome — NCT07804719 · active not recruiting · started 2025-07-20
- Safety and Efficacy of Klotho and Follistatin Gene Therapy — NCT07285629 · Early phase 1 · completed · started 2025-12-16
- Follistatin Levels in Metabolically Healthy and Unhealthy Obese Individuals — NCT06229899 · completed · started 2022-01-15
- Association of the Mediterranean Diet With Fertility Outcomes — NCT03050944 · completed · started 2013-06
- Phase I: Safety and Efficacy of an Injectable Follistatin Plasmid Gene Therapy in Humans — NCT06411366 · Phase 1 · completed · started 2022-08-18
What the evidence does not show
- Paper counts measure research attention, not whether Follistatin works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list Follistatin
None of the vendors in our directory listed Follistatin in their public catalog when we checked. The vendor directory records what each vendor publishes about testing.
Follistatin reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Follistatin FAQ
Is Follistatin FDA-approved?
Follistatin is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Is Follistatin safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Follistatin?
PubMed indexes 2,974 papers on Follistatin (90 tagged as clinical trials) as of October 19, 2026.
Who sells Follistatin?
None of the vendors in our directory listed it when we checked.
Related compounds
Follistatin-315GHRHGHRP-6SomatropinHexarelinMGFTesamorelinTesamorelin + CJC-1295 (no DAC) + ipamorelin blendAll growth hormone & ghrh