Not approved (research only)Follistatin isoformMuscle research
Follistatin-315
Follistatin-315 is a circulating isoform of follistatin, a myostatin- and activin-binding protein studied in muscle biology.
What is Follistatin-315?
Follistatin-315 is a circulating isoform of follistatin, a myostatin- and activin-binding protein studied in muscle biology. Follistatin-315 is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Key takeaways
- Follistatin-315 is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
- PubMed indexes 2,974 papers on Follistatin-315 (90 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 15 registered studies using Follistatin-315.
- No vendor in our directory listed Follistatin-315 when we checked.
Regulatory & access status
Follistatin-315 is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Follistatin-315?
PubMed indexes 2,974 papers mentioning Follistatin-315 in the title or abstract, 671 of them from the last five years and 90 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Follistatin. — Int J Biochem Cell Biol, 1998 · review
- Follistatin and follistatin-like 3 in metabolic disorders. — Prostaglandins Other Lipid Mediat, 2023 · review
- Deletion of fibro-adipogenic progenitors-specific follistatin impairs muscle function and accelerates skeletal muscle atrophy in obese mice. — Mol Med, 2025
- Follistatin: a multifunctional regulatory protein. — Front Neuroendocrinol, 1998 · review
- Follistatin-mediated vascular protection via inhibition of activin A in essential and secondary hypertension. — Hypertens Res, 2024
- Activin/follistatin and atherosclerosis--a review. — J Atheroscler Thromb, 1998 · review
Registered clinical studies
ClinicalTrials.gov lists 15 studies with Follistatin-315 as an intervention (see all). Most recent:
- Possible Sarcopenia, Sarcopenia, and Functional Status in Patients With Primary Sjögren's Syndrome — NCT07804719 · active not recruiting · started 2025-07-20
- Safety and Efficacy of Klotho and Follistatin Gene Therapy — NCT07285629 · Early phase 1 · completed · started 2025-12-16
- Follistatin Levels in Metabolically Healthy and Unhealthy Obese Individuals — NCT06229899 · completed · started 2022-01-15
- Association of the Mediterranean Diet With Fertility Outcomes — NCT03050944 · completed · started 2013-06
- Phase I: Safety and Efficacy of an Injectable Follistatin Plasmid Gene Therapy in Humans — NCT06411366 · Phase 1 · completed · started 2022-08-18
What the evidence does not show
- Paper counts measure research attention, not whether Follistatin-315 works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list Follistatin-315
None of the vendors in our directory listed Follistatin-315 in their public catalog when we checked. The vendor directory records what each vendor publishes about testing.
Follistatin-315 reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Follistatin-315 FAQ
Is Follistatin-315 FDA-approved?
Follistatin-315 is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Is Follistatin-315 safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Follistatin-315?
PubMed indexes 2,974 papers on Follistatin-315 (90 tagged as clinical trials) as of October 19, 2026.
Who sells Follistatin-315?
None of the vendors in our directory listed it when we checked.
Related compounds
FollistatinGHRHGHRP-6SomatropinHexarelinMGFTesamorelinTesamorelin + CJC-1295 (no DAC) + ipamorelin blendAll growth hormone & ghrh