FDA-approvedGnRH agonistProstate cancerpuberty
Triptorelin
Triptorelin is a GnRH agonist, FDA-approved as Trelstar for advanced prostate cancer and as Triptodur for central precocious puberty.
What is Triptorelin?
Triptorelin is a GnRH agonist, FDA-approved as Trelstar for advanced prostate cancer and as Triptodur for central precocious puberty. Triptorelin is an FDA-approved prescription medicine (TRELSTAR, TRIPTODUR KIT); "research use only" vials sold online are not the approved product.
Triptorelin is an oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone. It has a role as an antineoplastic agent, a contraceptive drug and a gonadotropin releasing hormone agonist.
Key takeaways
- Triptorelin is an FDA-approved prescription medicine (TRELSTAR, TRIPTODUR KIT); "research use only" vials sold online are not the approved product.
- PubMed indexes 1,005 papers on Triptorelin (254 tagged as clinical trials) as of October 19, 2026.
- ClinicalTrials.gov lists 298 registered studies using Triptorelin.
- 5 vendors in our directory listed Triptorelin in their public catalog on October 19, 2026.
Structure
Regulatory & access status
Triptorelin is an FDA-approved prescription medicine (TRELSTAR, TRIPTODUR KIT); "research use only" vials sold online are not the approved product.
- TRELSTAR — VERITY, application NDA021288 (prescription). Drugs@FDA
- TRELSTAR — VERITY, application NDA020715 (prescription). Drugs@FDA
- TRIPTODUR KIT — AZURITY, application NDA208956 (prescription). Drugs@FDA
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Triptorelin?
PubMed indexes 1,005 papers mentioning Triptorelin in the title or abstract, 229 of them from the last five years and 254 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Triptorelin. — , 2012 · review
- Triptorelin for the treatment of endometriosis. — Expert Opin Pharmacother, 2014 · review
- Triptorelin embonate (6-month formulation). — Drugs, 2010 · review
- Triptorelin pamoate (Trelstar). — Med Lett Drugs Ther, 2002
- [Pharmacodynamics of triptorelin]. — Rev Prat, 2005 · review
- Triptorelin associated adverse events evaluated using FAERS pharmacovigilance data. — Sci Rep, 2025
Registered clinical studies
ClinicalTrials.gov lists 298 studies with Triptorelin as an intervention (see all). Most recent:
- Long Protocol and Growth Hormone in Poor Responders — NCT02338206 · Phase 2 · completed · started 2015-03
- Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway — NCT07187947 · recruiting · started 2025-07-18
- A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer — NCT03332797 · Phase 1 · active not recruiting · started 2017-11-24
- Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer — NCT00936390 · Phase 3 · completed · started 2009-09
- Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility — NCT04071574 · Phase 1/Phase 2 · completed · started 2018-02-01
What the evidence does not show
- Paper counts measure research attention, not whether Triptorelin works or is safe.
Research suppliers that list Triptorelin
5 vendors in our directory listed a product matching Triptorelin in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
Prices per mg, where we could verify them, are on our price comparison.
Triptorelin reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Triptorelin FAQ
Is Triptorelin FDA-approved?
Triptorelin is an FDA-approved prescription medicine (TRELSTAR, TRIPTODUR KIT); "research use only" vials sold online are not the approved product.
Is Triptorelin safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Triptorelin?
PubMed indexes 1,005 papers on Triptorelin (254 tagged as clinical trials) as of October 19, 2026.
Who sells Triptorelin?
Biotech Peptides, Core Peptides, Extreme Peptides, Peptide Worldwide, Swiss Chems listed it on their public catalogs when we checked; a listing is not an endorsement.
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