PT-141 (bremelanotide)

Structure

Regulatory & access status

PT-141 (bremelanotide) is an FDA-approved prescription medicine (VYLEESI (AUTOINJECTOR)); "research use only" vials sold online are not the approved product.

• VYLEESI (AUTOINJECTOR) — COSETTE, application NDA210557 (prescription). Drugs@FDA

Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.

How much research exists on PT-141 (bremelanotide)?

PubMed indexes 95 papers mentioning PT-141 (bremelanotide) in the title or abstract, 52 of them from the last five years and 11 tagged as clinical trials (search run October 19, 2026; repeat the search).

Most relevant recent papers

• Bremelanotide. — , 2012 · review
• Bremelanotide. — , 2006 · review
• Bremelanotide: First Approval. — Drugs, 2019 · review
• Hypoactive Sexual Desire Disorder in Women: Physiology, Assessment, Diagnosis, and Treatment. — J Midwifery Womens Health, 2021 · review
• Bremelanotide for Treatment of Female Hypoactive Sexual Desire. — Neurol Int, 2022 · review
• Bremelanotide: New Drug Approved for Treating Hypoactive Sexual Desire Disorder. — Ann Pharmacother, 2020 · review

Registered clinical studies

ClinicalTrials.gov lists 10 studies with PT-141 (bremelanotide) as an intervention (see all). Most recent:

• Role of the Melanocortin-4 Receptor in Hypoactive Sexual Desire Disorder — NCT04179734 · Phase 4 · completed · started 2019-10-07
• A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity — NCT06565611 · Phase 2 · active not recruiting · started 2024-08-05
• 2. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder — NCT02338960 · Phase 3 · completed · started 2015-01
• A Phase 3, Bridging, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of Subcutaneously Administered Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder (With or Without Decreased Arousal) — NCT04943068 · Phase 3 · completed · started 2021-05-10
• Bremelanotide in Premenopausal Women With Female Sexual Arousal Disorder and/or Hypoactive Sexual Desire Disorder — NCT01382719 · Phase 2 · completed · started 2011-06

What the evidence does not show

• Paper counts measure research attention, not whether PT-141 works or is safe.

Research suppliers that list PT-141

39 vendors in our directory listed a product matching PT-141 in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.

• Amino AmigosCatalog item: “PT 141”
• Ascension PeptidesCatalog item: “PT-141 (10MG)”
• Atomik LabzCatalog item: “BULK PACK PT-141 – 10mg (10 VIALS)”
• Backroad AminosCatalog item: “PT-141 10mg”
• Biocollex ResearchCatalog item: “PT-141”
• BioGenix PeptidesCatalog item: “PT-141 10mg”
• Biotech PeptidesCatalog item: “PT-141 (Bremelanotide) (10mg)”
• Bulk Peptide SupplyCatalog item: “PT-141 (Bremelanotide) 10 mg”
• Core PeptidesCatalog item: “PT-141 (Bremelanotide) – 10MG”
• Dynamic PeptideCatalog item: “PT-141 Peptide 10mg”
• Eros PeptidesCatalog item: “PT-141 10MG”
• Evolve BioPepCatalog item: “PT-141 10mg”
• Extreme PeptidesCatalog item: “PT-141 (Bremelanotide)”
• Ion PeptideCatalog item: “PT-141 – 10mg”
• Liberty PeptidesCatalog item: “PT-141 (10mg)”
• Licensed PeptidesCatalog item: “PT-141 10mg (10 Vials)”
• LotusPeptideCatalog item: “PT-141 10mg”
• Modern AminosCatalog item: “PT-141 10MG”
• Paramount PeptidesCatalog item: “PT-141 (10mg)”
• Peptide CraftersCatalog item: “PT-141 (10mg)”
• Peptide PartnersCatalog item: “PT-141 (10mg vials)”
• Peptide WorldwideCatalog item: “PT-141 (Bremelanotide) – 10MG per vial”
• Peptide.ExpressCatalog item: “PT-141”
• Pharma Grade PeptidesCatalog item: “PT-141 10MG”
• Plum Labs ResearchCatalog item: “PT-141 10mg”
• Polaris PeptidesCatalog item: “PT-141 (Bremelanotide) 10mg”
• Prime Lab PeptidesCatalog item: “PT-141 – 10mg”
• ProtideHealthCatalog item: “PT-141 10mg”
• Pure Lab PeptidesCatalog item: “PT-141 10mg”
• Ramp PeptidesCatalog item: “PT-141 10mg”
• Royal PeptidesCatalog item: “PT-141 10mgx10vials”
• San Diego PeptidesCatalog item: “PT-141 (Bremelanotide)”
• Science.bioCatalog item: “PT-141 – Aliquot”
• Southern AminosCatalog item: “PT-141 10mg”
• Sports Technology LabsCatalog item: “PT-141 (Bremelanotide) 10 mg”
• Sunrise BioResearchCatalog item: “PT-141 10mg x 10vials, 100mg”
• Swiss ChemsCatalog item: “PT-141 (Bremelanotide), 10mg”
• Verified PeptidesCatalog item: “PT-141 Peptide (10MG)”
• Voltera SciencesCatalog item: “PT-141 10MG”

Prices per mg, where we could verify them, are on our price comparison.

PT-141 reconstitution math

Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.

PT-141 FAQ

Head-to-head comparisons

PT-141 vs Melanotan II

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