Not approved (research only)Melanocortin agonist peptideTanning research
Melanotan II
Melanotan II is a synthetic melanocortin-receptor agonist that darkens skin; it is unapproved and regulators have warned against its use.
What is Melanotan II?
Melanotan II is a synthetic melanocortin-receptor agonist that darkens skin; it is unapproved and regulators have warned against its use. Melanotan II is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Key takeaways
- Melanotan II is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
- PubMed indexes 196 papers on Melanotan II (4 tagged as clinical trials) as of October 19, 2026.
- 36 vendors in our directory listed Melanotan II in their public catalog on October 19, 2026.
Structure
Regulatory & access status
Melanotan II is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Sellers that market unapproved peptides for human use can receive FDA warning letters; our vendor directory links any letter we found on fda.gov.
How much research exists on Melanotan II?
PubMed indexes 196 papers mentioning Melanotan II in the title or abstract, 29 of them from the last five years and 4 tagged as clinical trials (search run October 19, 2026; repeat the search).
Most relevant recent papers
- Melanotan-II reverses memory impairment induced by a short-term HF diet. — Biomed Pharmacother, 2023
- Melanotan II: a possible cause of renal infarction: review of the literature and case report. — CEN Case Rep, 2020 · review
- Melanotan II User Experience: A Qualitative Study of Online Discussion Forums. — Dermatology, 2021
- CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists. — J Med Chem, 2022
- Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism. — PLoS One, 2019
- Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. — Neuroscience, 2006
What the evidence does not show
- Paper counts measure research attention, not whether Melanotan II works or is safe.
- No FDA review of any "research use only" product's identity, purity, sterility or dose.
Research suppliers that list Melanotan II
36 vendors in our directory listed a product matching Melanotan II in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.
- Ascension Peptides
- Atomik Labz
- Biocollex Research
- BioGenix Peptides
- Bulk Peptide Supply
- Core Peptides
- Dynamic Peptide
- Eros Peptides
- Evolve BioPep
- Extreme Peptides
- JetPeps
- Liberty Peptides
- Licensed Peptides
- LotusPeptide
- Modern Aminos
- NuScience Peptides
- Paramount Peptides
- Peptide Crafters
- Peptide Worldwide
- Peptide.Express
- Pharma Grade Peptides
- Pinnacle Peptide Labs
- Polaris Peptides
- Prime Lab Peptides
- Prime Peptides
- ProtideHealth
- Pure Lab Peptides
- Ramp Peptides
- San Diego Peptides
- Science.bio
- Southern Aminos
- Sports Technology Labs
- Sunrise BioResearch
- Swiss Chems
- Voltera Sciences
- Xcel Peptides
Prices per mg, where we could verify them, are on our price comparison.
Melanotan II reconstitution math
Lab arithmetic only, not dosing guidance: use the peptide calculator to turn a vial size and diluent volume into a concentration.
Melanotan II FAQ
Is Melanotan II FDA-approved?
Melanotan II is not approved by the FDA for any use; products sold under this name are labeled for research use only, not for human consumption.
Is Melanotan II safe?
Safety data come from the published studies listed on this page; read them in full. Products sold as "research use only" have no FDA review of their purity, sterility or dose.
How much research is there on Melanotan II?
PubMed indexes 196 papers on Melanotan II (4 tagged as clinical trials) as of October 19, 2026.
Who sells Melanotan II?
Ascension Peptides, Atomik Labz, Biocollex Research, BioGenix Peptides, Bulk Peptide Supply, Core Peptides and 30 more listed it on their public catalogs when we checked; a listing is not an endorsement.
Head-to-head comparisons
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