Lab arithmeticMGF (mechano growth factor)Not approved (research only)
MGF 5 mg: dosing evidence and reconstitution math
A 5 mg vial of MGF mixed with 2 mL of diluent is 2.5 mg/mL, so 10 units on a U-100 syringe (0.1 mL) contain 250 mcg.
Is there an established dose?
No FDA label or published human trial defines a dose of MGF, so we do not publish one. Online "protocols" for it are not evidence.
- MGF (mechano growth factor) profile: FDA status, research volume and registered trials.
5 mg vial concentration table
Concentration = vial content ÷ diluent volume. A U-100 insulin syringe holds 1 mL in 100 units, so 1 unit = 0.01 mL.
| Diluent | Concentration | Per 10 units (0.1 mL) | Per 1 unit |
|---|---|---|---|
| 1 mL | 5 mg/mL | 500 mcg | 50 mcg |
| 2 mL | 2.5 mg/mL | 250 mcg | 25 mcg |
| 3 mL | 1.667 mg/mL | 167 mcg | 16.7 mcg |
| 5 mL | 1 mg/mL | 100 mcg | 10 mcg |
Arithmetic only; it assumes the vial contains exactly what the label states. Independent tests often find vials under- or over-filled, which is why a lot's certificate of analysis matters.
Syringe units for a given amount
Units on a U-100 syringe needed to draw each amount from this 5 mg vial, by diluent volume. The amounts are fractions of the vial (1/50, 1/20, 1/10, 1/5), not dose suggestions.
| Amount | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 100 mcg | 2 units | 4 units | 6 units |
| 250 mcg | 5 units | 10 units | 15 units |
| 500 mcg | 10 units | 20 units | 30 units |
| 1 mg | 20 units | 40 units | 60 units |
Units = amount ÷ concentration × 100. Draws above 100 units exceed a 1 mL syringe.
What the research covers
A PubMed search for "mechano growth factor"[tiab] returned 194 records (19 from the last five years), 6 indexed as clinical trials when checked on October 2026.
- Mechano-growth factor regulates periodontal ligament stem cell proliferation and differentiation through Fyn-RhoA-YAP signaling.
- The role of mechano growth factor in chondrocytes and cartilage defects: a concise review.
- Mechano-growth factor E-domain modulates cardiac contractile function through 14-3-3 protein interactomes.
- Mechano growth factor interacts with nucleolin to protect against cisplatin-induced neurotoxicity.
- Mechano Growth Factor Accelerates ACL Repair and Improves Cell Mobility of Mechanically Injured Human ACL Fibroblasts by Targeting Rac1-PAK1/2 and RhoA-ROCK1 Pathways.
ClinicalTrials.gov lists 105 registered studies (search), including:
- Study of VF001-DP in Patients With Chronic Venous Leg Ulcers
- Patellar Tendinopathy - Effect of Training and Enhancement of the Collagen Synthesis by Insulin-like Growth Factor-I
- Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates
- Establishment of Reference Values for Insulin-like Growth Factor 1 (IGF1) in the General Population
Where research vials are listed
8 suppliers in our directory list MGF (A–Z): Biotech Peptides, Core Peptides, Extreme Peptides, Paramount Peptides, Peptide Worldwide, Pharma Grade Peptides, Pure Lab Peptides, Swiss Chems. A listing is not a quality endorsement; ask for a lot-specific certificate of analysis.
Storage & handling
Follow the storage statement on the product sheet or certificate of analysis. Lyophilized (freeze-dried) peptides are generally kept cold, dry and away from light; once reconstituted, stability is shorter and depends on the compound and diluent. Bacteriostatic water contains 0.9% benzyl alcohol as a preservative; sterile water does not.
Frequently asked questions
How much bacteriostatic water for a 5 mg MGF vial?
The diluent volume only sets the concentration: 1 mL gives 5 mg/mL, 2 mL gives 2.5 mg/mL and 3 mL gives 1.667 mg/mL. Smaller volumes are more concentrated, so each syringe unit holds more.
How much MGF is in 10 units?
At 2 mL of diluent, 10 units (0.1 mL) of a 5 mg vial contain 250 mcg; at 1 mL they contain 500 mcg.
What is the dose of MGF?
No FDA label or published human trial defines a dose of MGF, so we do not publish one. Online "protocols" for it are not evidence.
Related pages
Peptide calculator BAC water calculator Growth hormone & GHRH protocols