Ipamorelin

Structure

What makes Ipamorelin different?

Its selling point in the 1998 paper was selectivity — GH release without the cortisol and prolactin effects seen with earlier secretagogues.

How does Ipamorelin work?

Binds the growth hormone secretagogue receptor (ghrelin receptor) in the pituitary, triggering pulsatile GH release.

What the clinical evidence actually shows

• Raun et al., Eur J Endocrinol 1998: characterization in animal models.
• No large human efficacy trials for body composition or anti-aging uses were identified.

How much research exists on Ipamorelin?

PubMed indexes 51 papers mentioning Ipamorelin in the title or abstract, 12 of them from the last five years and 2 tagged as clinical trials (search run October 19, 2026; repeat the search).

Most relevant recent papers

• Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians. — Am J Sports Med, 2026 · review
• Ipamorelin, the first selective growth hormone secretagogue. — Eur J Endocrinol, 1998
• Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. — J Am Acad Orthop Surg Glob Res Rev, 2026 · review
• Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance. — Sports Med, 2026 · review
• Peptide Supplements and Their Therapeutic Applications in Sports Medicine. — Am J Sports Med, 2026
• Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives. — Int J Mol Sci, 2026 · review

Registered clinical studies

ClinicalTrials.gov lists 3 studies with Ipamorelin as an intervention (see all). Most recent:

• Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function — NCT01280344 · Phase 2 · completed · started 2011-04
• Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus — NCT00672074 · Phase 2 · completed · started 2008-04
• Trifecta Research Study — NCT07717866 · active not recruiting · started 2022-08-01

Side effects

Controlled human safety data are limited. GH-axis stimulation in general can affect glucose metabolism and fluid retention.

Regulatory & access status

• Not FDA-approved.

Sourcing & safety

Sold online as a research chemical; some clinics prescribe compounded versions.

Doses in labels and trials

Reference only — copied from published research. Not a recommendation.

What the evidence does not show

• Long-term benefit for muscle, fat loss or sleep in controlled human trials.
• Long-term safety.

Ipamorelin FAQ

Related peptides & comparisons

SermorelinTesamorelin Growth Hormone

References

1. Ipamorelin, the first selective growth hormone secretagogue, Eur J Endocrinol (1998), PMID 9849822
2. Ipamorelin — PubChem compound summary (CID 9831659), PubChem

Ipamorelin calculators

Lab arithmetic only: convert a mass to a volume or syringe units at a known concentration with the units converter, or work out a concentration with the reconstitution calculator.

Where to get Ipamorelin legally

There is no FDA-approved Ipamorelin product. Compounded versions depend on FDA's compounding rules, and "research use only" products are not for human use.

Get Ipamorelin via telehealth

None of the telehealth providers we have verified lists Ipamorelin.

Research suppliers that list Ipamorelin

41 vendors in our directory listed a product matching Ipamorelin in their public catalog on October 19, 2026. Listed alphabetically; a listing is not an endorsement. Research use only.

• Ascension PeptidesCatalog item: “Ipamorelin (5MG)”
• Atomik LabzCatalog item: “BULK PACK Ipamorelin – 10mg (10 VIALS)”
• Backroad AminosCatalog item: “Ipamorelin 10mg”
• BioGenix PeptidesCatalog item: “Ipamorelin 10mg”
• BioLongevity LabsCatalog item: “Ipamorelin (10mg)”
• Biotech PeptidesCatalog item: “Ipamorelin (5mg)”
• Bulk Peptide SupplyCatalog item: “Ipamorelin 10 mg”
• Core PeptidesCatalog item: “Ipamorelin – 5MG”
• CostidesCatalog item: “Ipamorelin 5 mg · 10-pack”
• Eros PeptidesCatalog item: “Ipamorelin 5MG”
• Evolve BioPepCatalog item: “Ipamorelin 10mg”
• Extreme PeptidesCatalog item: “Ipamorelin”
• JetPepsCatalog item: “Ipamorelin 10mg”
• Liberty PeptidesCatalog item: “Ipamorelin (5mg)”
• Licensed PeptidesCatalog item: “Ipamorelin 10mg (10 vials)”
• LotusPeptideCatalog item: “Ipamorelin 10mg”
• Modern AminosCatalog item: “Ipamorelin”
• NuScience PeptidesCatalog item: “Ipamorelin Peptide — 5mg | 10mg”
• OmegAminoCatalog item: “OmA – Ipamorelin”
• Paramount PeptidesCatalog item: “Ipamorelin (10mg)”
• Peptide CraftersCatalog item: “Ipamorelin (10mg)”
• Peptide PartnersCatalog item: “Ipamorelin (10mg vials)”
• Peptide WorldwideCatalog item: “Ipamorelon (Ipamorelin) – 2MG per vial”
• Peptide.ExpressCatalog item: “Ipamorelin 10mg”
• Pharma Grade PeptidesCatalog item: “Ipamorelin Peptide 10MG”
• Pinnacle Peptide LabsCatalog item: “Ipamorelin [10mg]”
• Polaris PeptidesCatalog item: “Ipamorelin 10mg”
• Prime Lab PeptidesCatalog item: “Ipamorelin – 10mg”
• Prime PeptidesCatalog item: “Ipamorelin”
• ProtideHealthCatalog item: “Ipamorelin 10mg”
• Pure Lab PeptidesCatalog item: “Ipamorelin 10mg”
• Ramp PeptidesCatalog item: “Ipamorelin 10 MG”
• Royal PeptidesCatalog item: “Ipamorelin 10mgx10vials”
• San Diego PeptidesCatalog item: “Ipamorelin”
• Science.bioCatalog item: “Ipamorelin – Aliquot, 5mg”
• Southern AminosCatalog item: “Ipamorelin 10mg”
• Sports Technology LabsCatalog item: “Ipamorelin 5 mg”
• Sunrise BioResearchCatalog item: “Ipamorelin 5mg x 10vials, 50mg”
• Swiss ChemsCatalog item: “Ipamorelin 2mg”
• Verified PeptidesCatalog item: “Ipamorelin Peptide (10MG)”
• Xcel PeptidesCatalog item: “Ipamorelin”

Prices per mg, where we could verify them, are on our price comparison.

Ipamorelin dosing protocol

There is no FDA-label or published-trial dosing schedule we can reproduce for Ipamorelin, so we don't publish one.

Find clinics offering Ipamorelin

• Ageless Health InstitutePhoenix, AZ — named on the clinic's own website
• 10X Health Clinic - ScottsdaleScottsdale, AZ — named on the clinic's own website
• Focal Point VitalityScottsdale, AZ — named on the clinic's own website
• Natural Radiance Aesthetics and WellnessScottsdale, AZ — named on the clinic's own website
• TransformyouTempe, AZ — named on the clinic's own website
• Edge Integrative WellnessTucson, AZ — named on the clinic's own website
• CQ Med GymLaguna Niguel, CA — named on the clinic's own website
• Leadwest Medical Weight Loss and Testosterone Longevity ClinicNewport Beach, CA — named on the clinic's own website
• OC WellnessNewport Beach, CA — named on the clinic's own website
• University Total WellnessSacramento, CA — named on the clinic's own website
• Viva WellnessSan Diego, CA — named on the clinic's own website
• Serenity Aesthetics & WellnessSan Francisco, CA — named on the clinic's own website

49 verified clinics name Ipamorelin; browse them by state.

Browse all clinics