Lab arithmetichMG (menotropins)FDA-approved
hMG 75 IU: dosing evidence and reconstitution math
A 75 IU vial of hMG mixed with 2 mL of diluent is 37.5 IU/mL, so 10 units on a U-100 syringe (0.1 mL) contain 3.75 IU.
Is there an established dose?
Doses of the FDA-approved product (MENOPUR) are set by its FDA label, linked below; research-grade vials are not that product.
- MENOPUR on Drugs@FDA (FERRING)
- hMG (menotropins) profile: FDA status, research volume and registered trials.
75 IU vial concentration table
Concentration = vial content ÷ diluent volume. A U-100 insulin syringe holds 1 mL in 100 units, so 1 unit = 0.01 mL.
| Diluent | Concentration | Per 10 units (0.1 mL) | Per 1 unit |
|---|---|---|---|
| 1 mL | 75 IU/mL | 7.5 IU | 0.75 IU |
| 2 mL | 37.5 IU/mL | 3.75 IU | 0.375 IU |
| 3 mL | 25 IU/mL | 2.5 IU | 0.25 IU |
| 5 mL | 15 IU/mL | 1.5 IU | 0.15 IU |
Arithmetic only; it assumes the vial contains exactly what the label states. Independent tests often find vials under- or over-filled, which is why a lot's certificate of analysis matters.
Syringe units for a given amount
Units on a U-100 syringe needed to draw each amount from this 75 IU vial, by diluent volume. The amounts are fractions of the vial (1/50, 1/20, 1/10, 1/5), not dose suggestions.
| Amount | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 1.5 IU | 2 units | 4 units | 6 units |
| 3.75 IU | 5 units | 10 units | 15 units |
| 7.5 IU | 10 units | 20 units | 30 units |
| 15 IU | 20 units | 40 units | 60 units |
Units = amount ÷ concentration × 100. Draws above 100 units exceed a 1 mL syringe.
What the research covers
A PubMed search for "menotropins"[tiab] returned 107 records (8 from the last five years), 13 indexed as clinical trials when checked on October 2026.
- Gonadotropins.
- Menotropins and sonography.
- The role of superovulation with menotropins in ovulatory infertility: a review.
- Early miscarriage and fetal malformations after induction of ovulation (by clomiphene citrate and/or human menotropins), in vitro fertilization, and gamete intrafallopian transfer.
- Quantitative determination of trace principal components with high specific activity in menotropins.
ClinicalTrials.gov lists 171 registered studies (search), including:
- Long Protocol and Growth Hormone in Poor Responders
- Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation
- GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia
- Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
Where research vials are listed
3 suppliers in our directory list hMG (A–Z): Peptide Worldwide, Pure Lab Peptides, Swiss Chems. A listing is not a quality endorsement; ask for a lot-specific certificate of analysis.
Storage & handling
Follow the storage statement on the product sheet or certificate of analysis. Lyophilized (freeze-dried) peptides are generally kept cold, dry and away from light; once reconstituted, stability is shorter and depends on the compound and diluent. Bacteriostatic water contains 0.9% benzyl alcohol as a preservative; sterile water does not.
Frequently asked questions
How much bacteriostatic water for a 75 IU hMG vial?
The diluent volume only sets the concentration: 1 mL gives 75 IU/mL, 2 mL gives 37.5 IU/mL and 3 mL gives 25 IU/mL. Smaller volumes are more concentrated, so each syringe unit holds more.
How much hMG is in 10 units?
At 2 mL of diluent, 10 units (0.1 mL) of a 75 IU vial contain 3.75 IU; at 1 mL they contain 7.5 IU.
What is the dose of hMG?
Doses of the FDA-approved product (MENOPUR) are set by its FDA label, linked below; research-grade vials are not that product.