Lab arithmetichCG (human chorionic gonadotropin)FDA-approved
hCG 5000 IU: dosing evidence and reconstitution math
A 5000 IU vial of hCG mixed with 2 mL of diluent is 2,500 IU/mL, so 10 units on a U-100 syringe (0.1 mL) contain 250 IU.
Is there an established dose?
Doses of the FDA-approved product (CHORIONIC GONADOTROPIN) are set by its FDA label, linked below; research-grade vials are not that product.
- CHORIONIC GONADOTROPIN on Drugs@FDA (FRESENIUS KABI USA)
- hCG (human chorionic gonadotropin) profile: FDA status, research volume and registered trials.
5000 IU vial concentration table
Concentration = vial content ÷ diluent volume. A U-100 insulin syringe holds 1 mL in 100 units, so 1 unit = 0.01 mL.
| Diluent | Concentration | Per 10 units (0.1 mL) | Per 1 unit |
|---|---|---|---|
| 2 mL | 2,500 IU/mL | 250 IU | 25 IU |
| 5 mL | 1,000 IU/mL | 100 IU | 10 IU |
| 10 mL | 500 IU/mL | 50 IU | 5 IU |
| 20 mL | 250 IU/mL | 25 IU | 2.5 IU |
Arithmetic only; it assumes the vial contains exactly what the label states. Independent tests often find vials under- or over-filled, which is why a lot's certificate of analysis matters.
Syringe units for a given amount
Units on a U-100 syringe needed to draw each amount from this 5000 IU vial, by diluent volume. The amounts are fractions of the vial (1/50, 1/20, 1/10, 1/5), not dose suggestions.
| Amount | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 100 IU | 2 units | 4 units | 6 units |
| 250 IU | 5 units | 10 units | 15 units |
| 500 IU | 10 units | 20 units | 30 units |
| 1,000 IU | 20 units | 40 units | 60 units |
Units = amount ÷ concentration × 100. Draws above 100 units exceed a 1 mL syringe.
What the research covers
A PubMed search for "chorionic gonadotropin"[tiab] returned 19,493 records (3,179 from the last five years), 780 indexed as clinical trials when checked on October 2026.
- Human Chorionic Gonadotropin (hCG)-An Endocrine, Regulator of Gestation and Cancer.
- Differential diagnosis of elevated human chorionic gonadotropin in women.
- Human Chorionic Gonadotropin and Early Embryogenesis: Review.
- [Chorionic gonadotropin].
- Human chorionic gonadotropin.
ClinicalTrials.gov lists 413 registered studies (search), including:
- Earlier Triggering in Rec-FSH/GnRH Antagonist Cycles
- A Trial to Investigate the Efficacy and Safety of FE 999302 as add-on Treatment to Follitropin Delta (REKOVELLE) in Women Undergoing Controlled Ovarian Stimulation.
- A Study Using Recombinant Human Luteinizing Hormone (r-hLH, Luveris®) in the Treatment of Chinese Women With Hypogonadotropic Hypogonadism
- Estradiol and Progesterone Levels Following Frozen Embryo Transfer
Where research vials are listed
11 suppliers in our directory list hCG (A–Z): Ascension Peptides, BioGenix Peptides, JetPeps, LotusPeptide, Peptide Worldwide, Peptide.Express, Pure Lab Peptides, Royal Peptides, and 3 more. A listing is not a quality endorsement; ask for a lot-specific certificate of analysis.
Storage & handling
Follow the storage statement on the product sheet or certificate of analysis. Lyophilized (freeze-dried) peptides are generally kept cold, dry and away from light; once reconstituted, stability is shorter and depends on the compound and diluent. Bacteriostatic water contains 0.9% benzyl alcohol as a preservative; sterile water does not.
Frequently asked questions
How much bacteriostatic water for a 5000 IU hCG vial?
The diluent volume only sets the concentration: 1 mL gives 5,000 IU/mL, 2 mL gives 2,500 IU/mL and 3 mL gives 1,667 IU/mL. Smaller volumes are more concentrated, so each syringe unit holds more.
How much hCG is in 10 units?
At 2 mL of diluent, 10 units (0.1 mL) of a 5000 IU vial contain 250 IU; at 1 mL they contain 500 IU.
What is the dose of hCG?
Doses of the FDA-approved product (CHORIONIC GONADOTROPIN) are set by its FDA label, linked below; research-grade vials are not that product.
Related pages
hCG 10000 IU vial math Peptide calculator BAC water calculator