Peptide Therapy Clinics in Sioux Falls, South Dakota
20 Sioux Falls practices that advertise peptide, GLP-1 or hormone care, ordered by how many of those services each one names. Read them alongside our telehealth and price data before you book.
| Clinic | ZIP | Services & terms on the clinic site | Evidence |
|---|---|---|---|
| Era Health | 57108 | Peptide therapy, GLP-1 weight loss, NAD+ therapy, Hormone therapy, Sermorelin | Page we read |
| Gameday Men's Health Sioux Falls, SD | 57110 | Peptide therapy, GLP-1 weight loss, NAD+ therapy, Hormone therapy, Sermorelin | Page we read |
| Limitless Male Medical Clinic | 57108 | Peptide therapy, GLP-1 weight loss, NAD+ therapy, Hormone therapy, Sermorelin | Page we read |
| Prime IV Hydration & Wellness - Sioux Falls | 57108 | Peptide therapy, GLP-1 weight loss, NAD+ therapy, Hormone therapy, Sermorelin | Page we read |
| Thrive & Co. | 57108 | Peptide therapy, GLP-1 weight loss, Hormone therapy, Sermorelin | Page we read |
| We Build Champions | 57108 | Peptide therapy, GLP-1 weight loss, NAD+ therapy, Hormone therapy | Page we read |
| Accelerate Wellness - Longevity Medicine Clinic | 57108 | Peptide therapy, GLP-1 weight loss, Hormone therapy | Page we read |
| Encompass Wellness & Aesthetics | 57108 | Peptide therapy, GLP-1 weight loss, Hormone therapy | Page we read |
| Liv Med Spa | Sioux Falls, SD | 57108 | Peptide therapy, GLP-1 weight loss, Hormone therapy | Page we read |
| LIVE Hydration Spa Sioux Falls | 57108 | GLP-1 weight loss, NAD+ therapy, Hormone therapy | Page we read |
| Peakform Wellness Clinic | 57108 | Peptide therapy, GLP-1 weight loss, Hormone therapy | Page we read |
| The Confidence Collective | 57108 | Peptide therapy, GLP-1 weight loss, NAD+ therapy | Page we read |
| Vital Flow Infusions | 57104 | GLP-1 weight loss, NAD+ therapy | Page we read |
| Avera Comprehensive Weight Management — 41st & Holbrook | 57106 | GLP-1 weight loss | Page we read |
| Functional Health Clinic | 57105 | GLP-1 weight loss | Page we read |
| Hormones Gone Wild | 57108 | Hormone therapy | Page we read |
| Novo Aesthetics | 57108 | GLP-1 weight loss | Page we read |
| Prairie Roots Health | 57108 | Hormone therapy | Page we read |
| Radiant Health and Hormone Therapy | 57110 | Hormone therapy | Page we read |
| Sioux Falls Secret for Weight Loss | 57105 | GLP-1 weight loss | Page we read |
No clinic lists that service. Choose “All”.
Sioux Falls at a glance
| Service | Clinics | Share |
|---|---|---|
| GLP-1 weight loss | 17 | 85% |
| Hormone therapy | 14 | 70% |
| Peptide therapy | 11 | 55% |
| NAD+ therapy | 8 | 40% |
| Sermorelin | 5 | 25% |
12 clinics list three or more of these services (Era Health, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, Prime IV Hydration & Wellness - Sioux Falls, Thrive & Co. and 7 more). 9 mention telehealth. Listings cover 5 ZIP codes (57104, 57105, 57106, 57108, 57110).
Clinic, telehealth or research vial: the three routes in Sioux Falls
People in Sioux Falls looking for GLP-1 or peptide treatment end up on one of three routes, and they differ more in regulation than in convenience. Of the 20 local clinics below, 17 advertise GLP-1 weight-loss care and 11 name peptide therapy; very few publish prices, so cost usually comes up only at the consultation.
| Route | What you get | Published cost evidence |
|---|---|---|
| Local clinic in Sioux Falls | In-person exam and labs; may prescribe brand-name or compounded drugs | Rarely published; ask whether the quote covers medication |
| Telehealth | Online prescriber licensed in your state; 4 of the 11 services we profile list only brand-name FDA-approved drugs | 4 of 11 publish prices on their own pages |
| Research vendors | Unapproved "research use only" vials; no prescriber, not for human use | Median $6.00/mg semaglutide (12 vendors), $5.05/mg tirzepatide (19 vendors), checked October 19, 2026 |
A low price per mg is not a like-for-like saving: research vials skip the manufacturing, sterility and dose checks that approved pens carry. See semaglutide prices per mg and tirzepatide prices per mg for the vendor-by-vendor data.
Clinics within 25 miles of Sioux Falls
Outside the city limits but close by: straight-line distance from the center of the Sioux Falls listings above.
Frequently asked questions
Where in Sioux Falls can I find GLP-1 weight loss?
On their own websites, Era Health, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, Prime IV Hydration & Wellness - Sioux Falls, Thrive & Co. and 12 more name GLP-1 weight loss (17 of 20). The source link in the table opens the page we quoted.
Where in Sioux Falls can I find hormone therapy?
On their own websites, Era Health, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, Prime IV Hydration & Wellness - Sioux Falls, Thrive & Co. and 9 more name hormone therapy (14 of 20). The source link in the table opens the page we quoted.
Can I see a Sioux Falls clinic online instead of in person?
Gameday Men's Health Sioux Falls, SD, Prime IV Hydration & Wellness - Sioux Falls, Thrive & Co., Accelerate Wellness - Longevity Medicine Clinic, Encompass Wellness & Aesthetics and 4 more advertise virtual visits. Expect labs or a first exam in person; national telehealth services are an alternative if you only need an FDA-approved GLP-1.
Where does this Sioux Falls list come from?
From the clinics themselves: on October 19, 2026 we opened each website and kept a service only where it is named. 19 of 20 print their street address, 19 their phone number, and 3 tie to a federal NPI organization record.
Nearby cities
All clinics statewide: South Dakota peptide clinics. FDA-approved peptides can also be prescribed through telehealth.